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Integrated Catalysis (iCAT) CDT

Student in white lab gear peering down a microscope, in front of a backdrop of beakers and molecule

Research projects

iCAT research projects connect the disciplines of chemocatalysis, chemical engineering and biocatalysis in creative ways to solve problems in molecule making.

Lewis Caiger

The iCAT programme lets me engage with the vast chemistry department at Manchester, allowing me to make a more educated choice when choosing which group I want to work with. I also think iCAT is an excellent opportunity as it encourages us to work at the borders of chemistry with other sciences to achieve important advances in science and sustainability.

Lewis Caiger / iCAT CDT student

iCAT supports interdisciplinary fundamental research in bio and chemocatalysis; projects include science and engineering aspects to ensure that the solutions developed are applicable and sustainable.

The portfolio of CDT projects on offer encompasses a diverse range of approaches to integrated catalysis, including:

  • synergistic chemo and biocatalysis cascades;
  • iCAT approaches to new chemical reactivity;
  • technology-driven solutions to iCAT system design;
  • reaction monitoring in bio and chemo catalysis systems;
  • integrating emerging areas of chemocatalysis (eg electro and photo catalysis) with biocatalysis;
  • smart catalysis and molecular robotics.

For their PhD research, cohort 1 students will be able to select from the projects listed below.

Cohort 1 PhD project titles

  • Development of dual catalysis systems for the preparation of peptide-drug conjugates
  • In-situ Nuclear Magnetic Resonance (NMR) studies of photocatalytic reactions for fine chemical production
  • Integrated Electro-Biocatalysis for Arylation
  • Design and Evolution of Photo-Enzymes for Stereoselective Transformations of Nitrogen Radicals
  • Merging transition metal-catalysis and electrochemistry for late stage functionalization of biologically active molecules
  • Iridium Knots for Allosterically-Controlled Dual Photoredox–Anion-Binding Catalysts
  • Development of asymmetric olefin amino-functionalizations via high-throughput experimentations
  • Activation of aromatic C-H bonds using a bio/chemocatalysis cascade approach
  • Base Metal Catalysed Dinitrogen Reduction and Fixation: Scope and Mechanisms
  • Merging Photocatalysis with Biocatalysis to Access Unexplored Chemical Space (hBIOCAT)
  • Integrating Biocatalysis and Metal-Mediated Radical Cyclizations for Diversity Oriented Synthesis
  • Process Intensification in Biocatalytic Silyl Transfers